Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behavior. M-AT Vu, EH Brown, MJ Wen, CA Noggle, Z Zhang, KJ Monk, S Bouabid, L Mroz, BM Graham, Y Zhuo, Y Li, TM Otchy, L Tian, IG Davison, DA Boas, MW Howe. Neuron 112 (6), 909-923.e9. 2024.
Editorial: Dopamine Neuron Diversity in Circuits and Diseases. J-F Poulin, TN Lerner, MW Howe. Frontiers in Neural Circuits, 16:856716. 2022.
Coordination of rapid cholinergic and dopaminergic signaling in striatum during spontaneous movement. M Howe, I Ridouh, AL Allegra Mascaro, A Larios, M Azcorra, DA Dombeck. Elife, 44903. 2019.
Rapid signalling in distinct dopaminergic axons during locomotion and reward.
MW Howe, DA Dombeck.
Nature 535 (7613), 505. 2016.
Prolonged dopamine signalling in striatum signals proximity and value of distant rewards.
MW Howe, PL Tierney, SG Sandberg, PEM Phillips, AM Graybiel.
Nature 500 (7464), 575. 2013.
Habit learning is associated with major shifts in frequencies of oscillatory activity and synchronized spike firing in striatum.
MW Howe, HE Atallah, A McCool, DJ Gibson, AM Graybiel.
Proceedings of the National Academy of Sciences, 201113158. 2011.
Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors.
T Patriarchi, JR Cho, K Merten, MW Howe, A Marley, WH Xiong, RW Folk, GJ Broussard, R Liang, MJ Jang, H Zhong, D Dombeck, M von Zastrow, A Nimmerjahn, V Gradinaru, JT Williams, L Tian.
Science, 4422. 2018.
Neurons in the ventral striatum exhibit cell-type-specific representations of outcome during learning.
HE Atallah, AD McCool, MW Howe, AM Graybiel.
Neuron 82 (5), 1145-1156. 2014.
Selective effects of dopamine depletion and L-DOPA therapy on learning-related firing dynamics of striatal neurons.
LF Hernandez, Y Kubota, D Hu, MW Howe, N Lemaire, AM Graybiel.
Journal of Neuroscience 33 (11), 4782-4795. 2013.
Effects of dopamine depletion on LFP oscillations in striatum are task-and learning-dependent and selectively reversed by L-DOPA.
N Lemaire, LF Hernandez, D Hu, Y Kubota, MW Howe, AM Graybiel.
Proceedings of the National Academy of Sciences, 201216403. 2012.
Differential dynamics of activity changes in dorsolateral and dorsomedial striatal loops during learning
CA Thorn, H Atallah, M Howe, AM Graybiel
Neuron 66 (5), 781-795. 2010.